nanoCLAMP SMT3-A1 is a single domain antibody mimetic recognizing yeast SUMO, human SUMO2, human SUMO3, SUMOstar and SUMO-tagged proteins. Validated applications include affinity chromatography and sandwich ELISA. nanoCLAMP SMT3-A1 anti-SUMO beads are useful for SUMO purification, SUMO immunoprecipitation (IP), SUMO pulldown, SUMO chromatography and SUMO isolation. nanoCLAMP SMT3-A1 represents an alternative to SUMO antibodies and SUMO nanobodies.  SMT3-A1 beads can be used for cleaved SUMO-tag removal from purified proteins.


Catalog No. Description Academic Price Commercial Price (including license fee) Quantity

nanoCLAMP SMT3-A1 recognizing yeast SUMO and human SUMO-2 and SUMO-3. Purified, lyophilized protein with unique C-terminal cysteine ready for conjugation. 10 nmol (180 ug).

$275 $525

Affinity chromatography resin for yeast SUMO and human SUMO-2 and SUMO-3. nanoCLAMP SMT3-A1 coupled to 6% agarose beads via thioether bond to C-terminal cysteine. Binding capacity of > 4.1 mg (175 nmol) SUMO-thioredoxin fusion per ml resin. 0.75 ml resin in 1.5 ml suspension. Useful for SUMO purification, SUMO immunoprecipitation (IP), SUMO chromatography, SUMO isolation, SUMO pulldown, SUMO removal, and SUMO depletion. Recognizes SUMO, SUMO-fusions and SUMO-tagged proteins.  Alternative to SUMO antibody beads and SUMO nanobody beads.

$475 $975

T7 expression plasmid for nanoCLAMP SMT3-A1. 200 ng lyophilized plasmid DNA

$65 $2000


Consensus Target
Confirmed Targets
Non-Reactive Targets
Biophysical Data
Binding Data
Extinction Coefficients
Variantε (280 nm)SolventDetermination Method
29,160 M-1cm-1
6 M Guanidine HCl
29,450 M-1cm-1


nanoCLAMP SMT3-A1(Cys) nanoCLAMP SMT3-A1 with N-terminal His-tag and C-terminal GS13 linker and unique Cys
nanoCLAMP SMT3-A1(Resin) SMT3-A1(Cys) coupled to Sulfolink™ resin
Reference Title PMID/ISBN
Suderman et al. 2017 Development of Polyol-Responsive Antibody Mimetics for Single-Step Protein Purification 28428153